Histologic tumor characteristic in breast cancer
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histologic characteristics the term metaplastic carcinoma was first introduced by huvos et al. Histologically, it is a poorly differentiated heterogeneous tumor containing ductal carcinoma cells admixed with areas of spindle, squamous, chondroid, or osseous elements. breast cancer is a heterogeneous disease, though little is known about some of its rarer forms, including certain histologic types. Using surveillance, epidemiology, and end results program data on 135 157 invasive breast cancer cases diagnosed from 1992 to 2001, relationships between nine histologic types of breast cancer and various tumour characteristics were assessed. breast cancers usually are epithelial tumors of ductal or lobular origin. The following features are all important in deciding on a course of treatment for any breast tumor size status of surgical margin presence or absence of estrogen receptors and progesterone receptors nuclear and histologic grade dna content s-phase fraction vascular. The histological workup for breast cancer diagnosis and treatment. The histological workup is the summary report of the pathologist. Essentially, breast cancer histology evaluation is the microscopic analysis of the chemical and cellular properties of the cells of a suspicious breast tumor. The pathologist will also confirm the size of the breast tumor where necessary for breast cancer. Histologic slides from representative series of breast cancer patients in boston, where the incidence rate of breast cancer is high, and in tokyo, where the incidence rate is low, were reviewed by pathologists who did not know the city of origin of the material. histological tumor grade is based on the degree of differentiation of the tumor tissue. In breast cancer, it refers to the semi-quantitative evaluation of morphological characteristics and is a relatively simple and low-cost method, requiring only adequately prepared hematoxylin-eosin-stained tumor tissue sections to be assessed by an. Hormone receptor status is related to the risk of breast cancer recurrence. Hormone receptor-positive tumors have a slightly lower risk of breast cancer recurrence than hormone receptor-negative tumors in the first 5 years after diagnosis. metaplastic breast cancer is a histological special type comprising tumours characterised by a complex admixture of adenocarcinomatous areas with metaplastic elements, which can be subdivided in homologous (i.). Unlike colon cancers, defining the progression of breast cancer has not been possible due to lack of markers that define hyperplasia (typical and atypical), carcinoma in situ and invasive cancer. 1 however, breast cancer can be broadly categorized into in situ carcinoma and invasive (infiltrating) carcinoma. Tumor grade is the description of a tumor based on how abnormal the tumor cells and the tumor tissue look under a microscope. It is an indicator of how quickly a tumor is likely to grow and spread. If the cells of the tumor and the organization of the tumors tissue are close to those of normal cells and tissue, the tumor is called well.
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